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Seroprevalence of Ebola virus infection in Bombali District, Sierra Leone

Nadege Goumkwa Mafopa, Gianluca Russo, Raoul Emeric Guetiya Wadoum, Emmanuel Iwerima, Vincent Batwala, Marta Giovanetti, Antonella Minutolo, Patrick Turay, Thomas B. Turay, Brima Kargbo, Massimo Amicosante, Mattei Maurizio, Carla Montesano, Ebola Study Group
  • Nadege Goumkwa Mafopa
    University of Dschang, Dschang, Cameroon; University of Makeni, Makeni, Sierra Leone; Holy Spirit Hospital, Maken, Sierra Leone
  • Gianluca Russo
    Holy Spirit Hospital, Makeni, Sierra Leone; La Sapienza University of Rome, Rome, Italy
  • Raoul Emeric Guetiya Wadoum
    University of Dschang, Dschang, Cameroon; University of Makeni, Makeni, Sierra Leone; Holy Spirit Hospital, Makeni, Sierra Leone; University of Rome Tor Vergata, Rome, Italy
  • Emmanuel Iwerima
    African Union Support to Ebola Outbreak in West Africa, Ethiopia
  • Vincent Batwala
    African Union Support to Ebola Outbreak in West Africa; Directorate of Research and Graduate Training, Mbarara University of Science and Technology, Uganda
  • Marta Giovanetti
    Holy Spirit Hospital, Makeni, Sierra Leone; University of Rome “Tor Vergata”, Rome, Italy
  • Antonella Minutolo
    Holy Spirit Hospital, Makeni, Sierra Leone; University of Rome “Tor Vergata”, Rome, Italy
  • Patrick Turay
    Holy Spirit Hospital, Makeni, Sierra Leone
  • Thomas B. Turay
    Partner Relief Development, Freetown, Sierra Leone
  • Brima Kargbo
    Ministry of Health and Sanitation, Freetown, Sierra Leone
  • Massimo Amicosante
    University of Rome “Tor Vergata”, Rome, Italy
  • Mattei Maurizio
    University of Rome “Tor Vergata”, Rome,
  • Ebola Study Group
    Affiliation not present

Abstract

A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of the 2013-2016 epidemic in West Africa may cause mild or asymptomatic infection in a proportion of cases, possibly due to an efficient immune response.

Keywords

Ebola, Serosurvey; anti-Ebola Zaire Virus Nucleoprotein IgG; Asymptomatic Ebola infection

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Submitted: 2017-06-30 10:17:35
Published: 2017-12-31 00:00:00
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Copyright (c) 2017 Carla Montesano, Nadege Goumkwa Mafopa, Gianluca Russo, Raoul Emeric Guetiya Wadoum, Emmanuel Iwerima, Vincent Batwala, Marta Giovanetti, Antonella Minutolo, Patrick Turay, Thomas B. Turay, Brima Kargbo, Massimo Amicosante, Mattei Maurizio

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